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 The Bleeding Disorders Association of the Southern Tier
 
(Member organization of the Hemophilia Federation of America)

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Hemophilia A & B are inherited genetic blood disorders resulting in impaired blood coagulation. They primarily affect males while being passed on by females who carry the hemophilia gene. Although rare, females may also have hemophilia. Most female carriers don't experience bleeding symptoms, however it is possible for female carriers to have low factor levels associated with bleeding problems.

HEMOPHILIA  A & B

Types of Hemophilia

There are 2 main types of Hemophilia

Hemophilia A - Factor VIII deficiency (the most common type)

Hemophilia B - Factor IX deficiency (less common)

Severity of Hemophilia

The severity of bleeding differs among patients depending on the level of clotting factor in the blood.

Severe - less than 1% of normal range of clotting factor; frequent bleeding can occur spontaneously or as a result of trauma, dental work or surgery.

Moderate - 1-5% of normal; experience less frequent problems, but also are at risk for bleeding after surgery/trauma.

Mild - 5-25%may go undetected until bleeding occurs following severe trauma or surgery.



1. Patients with a family history of blood disorders

2. When bleeding symptoms occur (frequent or excess bruising, swelling, etc)

Diagnosis

Is made by blood tests that measure the level of clotting factor VIII or IX. The levels generally remain unchanged throughout a lifetime, except for pregnant females where hormones raise the levels.

Treatment of Hemophilia

Replace missing clotting protein factor VIII and factor IX products. They are given intravenous pushover 10-15 minutes when bleeding occurs and on a regular basis if person is severe to prevent bleeding episodes.

Treatment used to rely only on human blood products but now synthetic clotting factors that are available offer a safer effective treatment.

Conservative treatment using ice, elevating affected extremity and use of crutches or splints. For children protective gear i.e. helmets/kneepads and elbow pads allow them to remain active but protected from injury.

Complications of Hemophilia

1. Joint Damage - This is a common complication die to repeated bleeding into various joints. It can lead to deformity if not treated adequately.

2. Viral Infections - blood products contaminated with HIV and hepatitis prior to donor screening caused transmission of viruses to hemophilia patients through Factor concentrates. Hemophilia treatment products are now manufactured using techniques to safeguard against viral transmission.

3. Post-op bleeding after surgery, if not treated or trauma.

For more specific and factual information on Hemophilia's A & B, including cause, symptoms, diagnosis, treatments, and more visit

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